Back to results
US 6,551,999 B1Granted
Angiogenesis inhibitor
AssigneeSenju Pharmaceutical Co., Ltd.
InventorsChiho Fukiage, Mitsuyoshi Azuma, Jun Inoue, Masayuki Nakamura, Yuka Yoshida
Life of this patent
Estimating the term…
Loading patent…
Loading patent…
AssigneeSenju Pharmaceutical Co., Ltd.
InventorsChiho Fukiage, Mitsuyoshi Azuma, Jun Inoue, Masayuki Nakamura, Yuka Yoshida
Estimating the term…
An angiogenesis inhibitor comprising a cysteine protease inhibitory compound. As the preferable cysteine protease inhibitory compound, epoxysuccinic acid compounds, peptide halohydrazide compounds, calpain inhibitory compounds, compounds of the formula (I) and compounds of the formula (VI) can be used. The angiogenesis inhibitor of the present invention suppresses new formation of blood vessels in the living tissues, so that it can be used as a superior therapeutic or prophylactic agent of angiogenesis associated with wound healing, inflammation, growth of tumor and the like; and angiogenesis as seen in diabetic retinopathy, prematurity retinopathy, retinal venous occlusion, senile discoid macular degeneration and the like, as well as for prevention of metastasis of tumors.
The compound N-(4-Fluorophenylsulfonyl)-L-valyl-L-leucinal or a salt thereof.
Dependencies are inferred from the claim text.