Retrovirus from the HIV group and its use
AssigneeDade Behring Marburg GmbH
InventorsLutz G. Guertler, Josef Eberle, Albrecht v. Brunn, Stefan Knapp, Hans-Peter Hauser
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Abstract
A novel immunodeficiency virus is disclosed which has the designation MVP-5180/91 and which has been deposited with the European Collection of Animal Cell Cultures (ECACC) under No. V 920 52 318. The characteristic antigens which can be obtained from it and which can be employed for detecting antibodies against retroviruses which are associated with immunodeficiency diseases are also disclosed, as are the DNA and amino acid sequences of the virus.
Claims22
A process for detection of antibodies that specifically bind to at least one HIV retrovirus, said process comprising
- providing a sample containing at least one antibody obtained from a patient suspected of being infected with an HIV virus;
- providing at least one peptide comprising an amino acid sequence encoded by the genome of virus MvP-5180/91 (SEQ ID NO:56);
- combining said sample and said at least one peptide under conditions where said at least one peptide and said at least one antibody can specifically bind to each other;
- and
- determining whether said at least one peptide and said at least one antibody specifically bound to each other.
Dependencies are inferred from the claim text.