Universal container for medicinal purpose

A container for in situ freeze-drying of a liquid medicinal preparation, said container comprising a casing section (1) with a bottom portion (3) and an outlet portion (2), wherein the casing section (1), the bottom portion (3) and the outlet portion (2) each consist of glass and the casing section (1) is thin-walled in comparison to all sections of the bottom portion (3), the outlet portion (2) is formed so as to be closable by a closure device, the bottom portion has a nonuniform geometry and

• wherein said bottom portion (3) is provided with at least one interior depression (3b), a reinforced section (3a) that is thicker than the at least one interior depression (3b), and
• wherein said reinforced section (3a) consists of a central reinforced region and a peripheral reinforced region concentric to said central reinforced region and said at least one interior depression (3b) consists of a circumferential rotationally symmetric depression between said peripheral reinforced region and said central reinforced region;
• wherein said bottom portion (3) has an outer bottom surface (3o) that is completely planar or planar with a comparatively slight central indentation (3c) so that sufficient surface contact is possible between said bottom surface (3o) and a cooling plate of a lyophilization device,
• whereby uniform crystalline freeze-drying of a liquid medicine contained in said container takes place during said freeze-drying with said lyophilization device.

A container for in situ freeze-drying of a liquid medicinal preparation, said container comprising a casing section (1) with a bottom portion (3) and an outlet portion (2), wherein the casing section (1), the bottom portion (3) and the outlet portion (2) each consist of glass and the casing section (1) is thin-walled in comparison to all sections of the bottom portion (3), the outlet portion (2) is formed so as to be closable by a closure device, the bottom portion has a nonuniform geometry and

• wherein said bottom portion (3) is provided with at least one interior depression (3b), a reinforced section (3a) that is thicker than the at least one interior depression (3b), and
• wherein said reinforced section (3a) consists of a pedestal-shaped central reinforced region and said at least one interior depression (3b) consists of a peripheral rotationally symmetric depressed region extending around said pedestal-shaped central reinforced region;
• wherein said bottom portion (3) has an outer bottom surface (3o) that is completely planar or planar with a comparatively slight central indentation (3c) so that sufficient surface contact is possible between said bottom surface (3o) and a cooling plate of a lyophilization device,
• whereby uniform crystalline freeze-drying of a liquid medicine contained in said container takes place during said freeze-drying with said lyophilization device.