US 6,551,610 B2 · Multifaceted compositions for post-surgical adhesion prevention

Abstract

This invention deals with an absorbable, gel-forming composition for multifaceted prevention of post-operative surgical adhesion through a plurality of physico-pharmacological modes, comprising a solution of one or more bioactive compounds in a liquid copolymeric vehicle made by end-grafting one or more cyclic monomer onto a polyalkylene glycol. More specifically, the bioactive drugs can display one or more pharmacological activity associated with antiangiogenic, antineoplastic, anti-inflammatory, and anti-proliferative effects.

Claims22

Dependent claims

An absorbable, liquid, gel-forming composition for multifaceted prevention of post-operative surgical adhesion through a plurality of physicopharmacological modes comprising a solution of one or more bioactive compound in a copolymerization product of polyalkylene glycol end-grafted with one or more cyclic monomer.

Dependencies are inferred from the claim text.

Facts

Application

10/131,657Filed 24 Apr 2002 · continuation in part

Priority

13 Apr 1995

Published

US 2002/0164365 A17 Nov 2002

Granted

22 Apr 2003

Term ends

Not estimatedThe source records don’t support an estimate.

Classification16 codes

A61K 9/0024
Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in…
A61K 47/34
Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates: macromolecular compounds obtained otherwise than by reactions only…
A61K 47/593
Obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes: polyesters, e.g. PLGA or…
A61K 47/60
Obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes: the organic…

Family

Application08/421,222Parent of this division · filed 13 Apr 1995

Application08/740,646Parent of this continuation-in-part · filed 31 Oct 1996

Application09/016,439Parent of this continuation-in-part · filed 29 Jan 1998

US 2002/0164365 A1Pre-grant publication · published 7 Nov 2002

US 6,413,539 B1Parent of this continuation-in-part

US 5,714,159 AParent of this continuation-in-part

Application08/740,646Parent of this division

US 5,612,052 AParent of this division

US 6,551,610 B2This patent

From the US filing history. Foreign family members aren’t listed.

Abstract

Facts

Application

10/131,657Filed 24 Apr 2002 · continuation in part

Priority

13 Apr 1995

Published

US 2002/0164365 A17 Nov 2002

Granted

22 Apr 2003

Term ends

Not estimatedThe source records don’t support an estimate.

Classification16 codes

A61K 9/0024
Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in…
A61K 47/34
Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates: macromolecular compounds obtained otherwise than by reactions only…
A61K 47/593
Obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes: polyesters, e.g. PLGA or…
A61K 47/60
Obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes: the organic…

Family

Application08/421,222Parent of this division · filed 13 Apr 1995

Application08/740,646Parent of this continuation-in-part · filed 31 Oct 1996

Application09/016,439Parent of this continuation-in-part · filed 29 Jan 1998

US 2002/0164365 A1Pre-grant publication · published 7 Nov 2002

US 6,413,539 B1Parent of this continuation-in-part

US 5,714,159 AParent of this continuation-in-part

Application08/740,646Parent of this division

US 5,612,052 AParent of this division

US 6,551,610 B2This patent

From the US filing history. Foreign family members aren’t listed.

Multifaceted compositions for post-surgical adhesion prevention

Life of this patent

Abstract

Claims22

Multifaceted compositions for post-surgical adhesion prevention

Life of this patent

Abstract

Claims22