Topical spray for burn treatment and anti-infection
AssigneeSage Pharmaceuticals, Inc.
InventorJivn-Ren Chen
Life of this patent
Estimating the term…
Abstract
This invention relates to a topical spray preparation for burn treatment and microbial infections on human being or animals. This non-aerosol preparation contains an antimicrobial drug, i.e., silver sulfadiazine, as is dispersed or solubilized in a cream or lotion base matrix which can be sprayed directly from a common trigger spray device. The key component of the matrix can be characterized by it having a suitable molecular weight polymer of cross-linked acrylic acid, such as Carbomers or non-ionic surfactants such as polyoxyethylene alkyl ethers, or any combination of the above materials.
Claims4
A non-aerosol spray system for burn treatment and anti-infection on a human being or an animal comprises:
- (a) a hand or finger trigger sprayable hydrophilic matrix composition;
- wherein the hydrophilic matrix composition comprises:
- (i) a bisbiguanide salt or a micronized sulfonamide salt;
- (ii) about 0.1 to about 25% of a hydrophilic base, wherein the hydrophilic base is about 0.1 to about 2% of cross-linked acrylic acid polymer or polymers with about 0.1 to about 2% of alkaline solution or about 1 to about 25% of polyoxyethylene alkyl ether or ethers, wherein the cross-linked acrylic acid polymer is Carbomer 934, Carbomer 940, or Carbomer 941, wherein the alkaline solution is about 25% of sodium hydroxide solution or strong ammonia solution;
- (ii) about 3 to about 40% of a humectant;
- (iii) about 0.1 to about 1% of a preservative;
- and
- (iv) suitable amount of purified water to adjust to 100%;
- and
- (b) a hand or finger trigger activated pump spray device designed to spray a wide or narrow spray patten.
Dependencies are inferred from the claim text.