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US 6,551,532 B1Granted
Method and device for forming particles
AssigneeAstraZeneca AB
InventorsCatherine Boissier, Håkan Glad
Life of this patent
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AssigneeAstraZeneca AB
InventorsCatherine Boissier, Håkan Glad
Estimating the term…
The present invention relates to a method for forming particles of a substance, comprising the step of introducing into a mixing chamber (8), in which the temperature and pressure are controlled, a fluid gas (4) and at least one vehicle system (1) comprising at least one substance in solution or suspension such that droplet formation and extraction of the vehicle occur substantially simultaneously by the action of the fluid gas (4). Turbulence is induced in at least one of said fluid gas (4) and said vehicle system (1) so as to create a controlled disorder in the flow of the at least one of the fluid gas (4) or the vehicle system (1) in order to control the particle formation in said mixing chamber (8), said controlled disorder being created by at least one flow perturbation means (11). The invention also relates to a mixing chamber having at least one flow perturbation means (11) that is disposed for interacting with at least one of a fluid gas (4) or vehicle system (1) supplied by the at least one supply member (4, 5) so as to induce turbulence or limited disorder in the at least one of the fluid gas (4) or vehicle system (1).
A method for forming particles of a substance, comprising the step of introducing into a mixing chamber, in which the temperature and pressure are controlled, a fluid gas and at least one vehicle system comprising at least one substance in solution or suspension such that droplet formation and extraction of the vehicle occur substantially simultaneously by the action of the fluid gas;
A mixing chamber for forming particles of a substance, said mixing chamber comprising a chamber having an inlet for receiving at least one first supply member having an outlet for supplying a fluid gas and at least one second supply member having an outlet for supplying a vehicle system comprising at least one substance in solution or suspension, and an outlet for exhausting the particles formed therein, wherein at least one flow perturbation means is disposed in the interior of the mixing chamber or is disposed in at least one of the passageways leading the fluids to the chamber for interacting with at least one of the fluid gas or vehicle system supplied by the at least one supply member to induce turbulence in the at least one of the fluid gas or vehicle system for creating a controlled disorder in the flow of the at least one of the fluid gas or the vehicle system in order to control the particle formation in said mixing chamber.
Dependencies are inferred from the claim text.