Adapter for mixing and injection of preparations

An adapter for mixing and injection of preparations comprising:

• a vial-fitting portion having a top wall and a skirt portion;
• a puncture needle passed through the top wall of the vial-fitting portion and integrated therewith, said puncture needle having a cutting edge on the side of said skirt;
• and
• a tubular tip-fitting portion located coaxially to the puncture needle on the opposite side thereof to the top wall,
• wherein said puncture needle has at a proximal end thereof a connecting portion for connection with the tip-fitting portion and a liquid passage which communicates with a lumen of the tip-fitting portion and is open to the cutting edge of the puncture needle, said connecting portion being provided at a liquid passage thereof with a first filter, said first filter being formed into a substantially spherical body so that orientation of said first filter is not necessary when arranging said first filter in said connecting portion.