A transmission electron microscope apparatus including an electrostatic lens that applies an accelerating voltage to an electron beam generated from an electron source, a specimen stage holding a specimen, a condenser lens and an objective lens provided so that said electron beam is focused on said specimen, a projection lens that enlarges the transmission image obtained by passing said electron beam through said specimen, an image acquisition apparatus that detects said enlarged transmission image, said transmission electron microscope apparatus comprising:
- a setting device for setting a plurality of inclination conditions of said electron beam being irradiated on said specimen with different desired deflecting angles (α, θ) representing a combination of an angle of incidence α and an orientation angle θ;
- a deflection coil for sequentially deflecting said electron beam which is irradiated with said different desired deflecting angles (α, θ) according to said inclination conditions;
- and
- a shift coil for shifting said electron beam deflected by said deflection coil so as to automatically focus said electron beam on substantially a same position on said image acquisition apparatus;
- wherein a good or no good condition of said specimen is inspected by comparing an output of said image acquisition apparatus with a reference image previously stored.