Retrovirus from the HIV type O and its use (MVP-2901/94)
AssigneeDade Behring Marburg GmbH
InventorsHans-Peter Hauser, Stefan Knapp, Stefan Brust, Lutz G. Gürtler, Josef Eberle, Lazare Kaptue, Léopold Achengui Zekeng
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Abstract
A novel HIV type O immunodeficiency virus is disclosed which has the designation MVP-2901/94 and which has been deposited with the European Collection of Animal Cell Cultures (ECACC) under No. V 950121601. The characteristic antigens which can be obtained from the virus and which can be employed for detecting antibodies against retroviruses which are associated with immunodeficiency diseases are also disclosed, as are the partial DNA and amino acid sequences of the virus.
Claims16
An isolated protein or polypeptide encoded by an isolated virus wherein said isolated protein or polypeptide binds with an antibody that binds to a polypeptide consisting of the amino acid sequence of positions 319-341 in SEQ ID NO:
- 12.
A test kit for detecting an antibody which binds with human immunodeficiency virus in a sample, comprising (1) a polypeptide comprising the amino acid sequence set forth in SEQ ID NO:12 and (2) a substance which specifically binds to an antibody which binds to said polypeptide.
A test kit for detecting an antibody that binds to human immunodeficiency virus in a sample, said kit comprising (1) an isolated virus that binds to antibodies that bind to a polypeptide consisting of the amino acid sequence at positions 319-341 in SEQ ID NO:
- 12 and (2) a substance which specifically binds to the antibody that binds to the isolated virus.
Dependencies are inferred from the claim text.