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US 6,548,607 B2Granted
High density, miniaturized arrays and methods of manufacturing same
Assignee3M Innovative Properties Company
InventorsKurt J. Halverson, Sanjay L. Patil, Jerald K. Rasmussen
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Abstract
High-density, miniaturized arrays including high surface areas. Arrays described include substrate with a coating of linking agents, as well as arrays with reactants affixed to the substrates. Methods of manufacturing high-density arrays of reactants. The methods include the use of oriented, heat shrink films and elastomeric materials. Methods of functionalizing a substrate with linking agents for subsequent affixation of reactants are also disclosed herein.
Claims9
A method of manufacturing an array, comprising:
- providing an oriented polymeric substrate;
- applying a coating comprising linking agents on said polymeric substrate;
- affixing reactants thereto to form binding sites;
- and
- relaxing the substrate, wherein the coating has a topographical surface area and a projected surface area and said topographical surface area is greater than said projected surface area.
2 more elements
A method of manufacturing a blank array, comprising:
- a. stretching an elastomeric material having at least one major surface with a surface area;
- and
- b. functionalizing the major surface, thereby creating linking agents on said substrate for ultimate affixation of a reactant.
Dependencies are inferred from the claim text.