Vision through photodynamic therapy of the eye
AssigneesQLT Inc., Novartis AG
InventorsH. Andrew Strong, Julia Levy, Gustav Huber, Mario Fsadni
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Abstract
Photodynamic therapy of conditions of the eye, especially those conditions characterized by unwanted neovasculature, such as age-related macular degeneration, results in enhanced visual acuity for treated subjects.
Claims20
A method to improve visual acuity in a human subject afflicted with unwanted neovasculature in ocular tissue comprising
- irradiating the ocular tissue of said human subject with light emitted from a laser,
- wherein said subject has been identified as in need of improvement in visual acuity and suffering from unwanted neovasculature in ocular tissue, and administered a formulation of a purpurin sufficient to permit an effective amount to localize in said ocular tissue;
- wherein said irradiation is with light containing a wavelength absorbed by the purpurin and is conducted for a time and at an intensity sufficient to improve visual acuity in said subject.
A method to improve visual acuity in a human subject afflicted with unwanted neovasculature in ocular tissue comprising
- administering a formulation of a purpurin sufficient to permit an effective amount to localize in the ocular tissue of a human subject identified as in need of improvement in visual acuity and suffering from unwanted neovasculature in ocular tissue, and
- irradiating the ocular tissue with light emitted from a laser;
- wherein said irradiation is with light containing a wavelength absorbed by the purpurin and is conducted for a time and at an intensity sufficient to improve visual acuity in said subject.
A method to improve visual acuity in a human subject afflicted with unwanted neovasculature in ocular tissue comprising
- identifying,a human subject in need of improvement in visual acuity and suffering from unwanted neovasculature in ocular tissue,
- administering a formulation of a purpurin sufficient to permit an effective amount to localize in said ocular tissue,
- irradiating said ocular tissue in said subject with light emitted from a laser
- wherein said irradiation is with light containing a wavelength absorbed by the purpurin and is conducted for a time and at an intensity sufficient to improve visual acuity in said subject.
A method to improve visual acuity in a human subject afflicted with unwanted neovasculature in ocular tissue comprising
- irradiating the ocular tissue of said human subject with light emitted from a laser,
- wherein said subject has been identified as in need of improvement in visual acuity and suffering from unwanted neovasculature in ocular tissue, and administered a formulation of a photoactive compound sufficient to permit an effective amount to localize in said ocular tissue;
- wherein said irradiation is with light containing a wavelength absorbed by the photoactive compound and is conducted for a time and at an intensity sufficient to improve visual acuity in said subject.
Dependencies are inferred from the claim text.