Complex of lipo-viro-particles, method of preparation and applications
AssigneesBio Merieux, Institut National de la Sante et de Recherche Medicale
InventorsPatrice André, Vincent Lotteau, Glaucia Paranhos-Baccala, Florence Komurian-Pradel
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Abstract
The complex consists of LVPs associated with human immunoglobulins having a density of less than 1.063 g/ml. It may be obtained by a method according to which a plasma or serum sample taken from a patient infected with HCV is made available, the LVPs are separated from the said sample by centrifugation according to their density, and the LVPs associated with human immunoglobulins are separated using protein A, anti-human immunoglobulins or any other molecule capable of binding human immunoglobulins.
Claims27
Complex consisting of lipo-viro particles (LVPs) associated with human immunoglobulins having a density of less than 1.063 g/ml.
Method for preparing a complex consisting of lipo-viro particles (LVPs) associated with human immunoglobulins and having a density of less than 1.063 g/ml, preferably of between 1.0063 and 1.063 g/ml, according to which:
- a plasma or serum sample from a patient infected with HCV is made available,
- the LVPs are separated from the sample by centrifugation according to their density, and
- the LVPs associated with human immunoglobulins are separated using protein A, anti-human immunoglobulins or any other molecule that binds human immunoglobulins.
Dependencies are inferred from the claim text.