Histidine kinase
AssigneeSmithKline Beecham Corporation
InventorsKaren M O'Dwyer, Deborah D Jaworski, Jeffrey L Mooney, Lisa K Shilling, John Peter Throup, Nicola Gail Wallis, Yi Yi Zhong, Min Wang
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Abstract
The invention provides Histidine Kinase polypeptides and polynucleotides encoding Histidine Kinase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Histidine Kinase polypeptides to screen for antibacterial compounds.
Claims7
An isolated polypeptide comprising SEQ ID NO:2, wherein the isolated polypeptide exhibits histidine kinase activity.
An isolated polypeptide comprising a fragment of SEQ ID NO:2 comprising at least 50 consecutive amino acids of SEQ ID NO:2;
- wherein said fragment exhibits histidine kinase activity.
An isolated polypeptide comprising a fragment of SEQ ID NO:2 comprising at least 30 consecutive amino acids of SEQ ID NO:2;
- wherein said fragment exhibits histidine kinase activity.
Dependencies are inferred from the claim text.