Moxifloxacin formulation containing common salt
AssigneeBayer Aktiengesellschaft
InventorsBernd Kühn, Hans-Friedrich Mahler, Michael Eisele
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Abstract
The present invention relates to an aqueous formulation comprising moxifloxacin hydrochloride and sodium chloride, to the formulation for use as a medicament and to the use of the formulation for preparing a medicament for preventing or treating bacterial infections in humans or animals.
Claims11
Aqueous formulation, comprising from 0.04% to 0.4% (w/v) (based on the amount of moxifloxacin) of moxifloxacin hydrochloride and from 0.4% to 0.9% (w/v) of sodium chloride.
Process for preparing the aqueous formulation of moxifloxacin hydrochloride, in which a solution of the moxifloxacin hydrochloride in water is prepared initially, and sodium chloride is then added and dissolved.
A method of treating or preventing a disease comprising administering to a host in need thereof an effective amount of an aqueous solution of moxifloxacin hydrochloride in water having a moxifloxacin hydrochloride concentration (based on the amount of moxifloxacin) of from more than 0.4% (w/v) to 2.4% (w/v).
A combination preparation comprising an aqueous solution of moxifloxacin hydrochloride in water having a moxifloxacin hydrochloride concentration (based on the amount of moxifloxacin) of from more than 0.4% (w/v) to 2.4% (w/v) and an aqueous solution comprising sodium chloride, wherein said solutions are separated from one another.
Dependencies are inferred from the claim text.