Murine interferon-α
AssigneeZymoGenetics, Inc.
InventorsScott R. Presnell, Andrew L. Feldhaus, Zeren Gao
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Abstract
Interferons represent an important class of biopharmaceutical products, which have a proven track record in the treatment of a variety of medical conditions, including the treatment of certain autoimmune diseases, the treatment of particular cancers, and the enhancement of the immune response against infectious agents. The present invention provides a new form of murine interferon-α, which has applications in diagnosis and therapy.
Claims7
An isolated polypeptide comprising the amino acid sequence consisting of amino acid residues 22 to 199 of SEQ ID NO:2.
An isolated polypeptide comprising an amino acid sequence that is a variant of amino acid residues 22 to 199 of SEQ ID NO:2, wherein any difference between amino acid residues 22 to 199 of SEQ ID NO:2 and the corresponding amino acid sequence of the variant is due to a conservative amino acid substitution, and wherein the isolated polypeptide exhibits anti-viral activity or anti-proliferative activity.
An isolated polypeptide having an amino acid sequence consisting of the amino acid sequence SEQ ID NO:2.
Dependencies are inferred from the claim text.