Lipopeptide stabilized microbubbles as diagnostic/therapeutic agents
AssigneeAmersham Health AS
InventorsAlan Cuthbertson, Magne Solbakken, Henry Raphael Wolfe
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Abstract
Novel membrane-forming amphiphilic lipopeptides comprising one or more peptide moieties containing 2-50 aminoacyl residues and one or more hydrocarbon chains containing 5-50 carbon atoms. Such lipopeptides may be used in the formation of stabilized gas microbubble dispersions suitable for use as diagnostic and/or therapeutic agents, for example as ultrasound contrast agents.
Claims14
A diagnostic and/or therapeutically active agent comprising encapsulated gas filled microbubbles stabilised by membrane-forming amphiphilic lipopeptides, wherein the peptide moieties of said lipopeptides each comprises less than 20 amino acid residues.
Dependencies are inferred from the claim text.