# US 6,537,314 B2 · Percutaneous mitral annuloplasty and cardiac reinforcement > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 6,537,314 B2 - Document ID: US6537314B2 - Status: Granted - Kind: B2 - Application number: 09/774,869 - Filed: 2001-01-30 - Published: 2002-08-01 - Granted: 2003-03-25 - Earliest claimed: 2000-01-31 - Assignees: ev3 Santa Rosa, Inc. - Inventors: Jonathan J. Langberg; Michael D. Lesh; Erik van der Burg - Web page: https://patentgrep.com/patent/US6537314B2 ## CPC - A61F 2/2451: {Inserts in the coronary sinus for correcting the valve shape} - A61F 2/2466: {Delivery devices therefor} - A61N 2001/0585: {Coronary sinus electrodes} - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) - A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B) ## Abstract A mitral annuloplasty and left ventricle restriction device is designed to be transvenously advanced and deployed within the coronary sinus and in some embodiments other coronary veins. The device places tension on adjacent structures, reducing the diameter and/or limiting expansion of the mitral annulus and/or limiting diastolic expansion of the left ventricle. These effects may be beneficial for patients with dilated cardiomyopathy. ## Claims ### Claim 1 An implant for positioning within a vessel to influence tissue outside of the vessel, comprising: an elongate, flexible body, having a proximal end and a distal end, each of the proximal and distal ends dimensioned to reside completely within the vascular system; and a forming element attached within the body, the forming element comprising a polymeric strand; wherein rotation of at least a portion of the forming element with respect to the body changes the shape of the body from an implantation configuration to a remodeling configuration, wherein at least a portion of the forming element remains attached to the body following implantation. ### Claim 2 (depends on 1) An implant as in claim 1, wherein the body is reversibly movable between an implantation configuration for transluminal implantation and a remodeling configuration for exerting a force against a vessel wall. ### Claim 3 (depends on 2) An implant as in claim 2, wherein the body defines an arc when in the remodeling configuration. ### Claim 4 (depends on 3) An implant as in claim 3, wherein a best fit constant radius curve corresponding to the arc has a radius within the range of from about 10 mm to about 20 mm. ### Claim 5 (depends on 1) An implant as in claim 1, further comprising a lock for retaining the body in the remodeling configuration. ### Claim 6 (depends on 5) An implant as in claim 5, wherein the lock comprises a locking ring. ### Claim 7 (depends on 5) An implant as in claim 5, wherein the lock comprises an interference fit. ### Claim 8 (depends on 5) An implant as in claim 5, wherein the lock comprises an adhesive bond. ### Claim 9 (depends on 5) An implant as in claim 5, wherein the lock comprises a suture knot. ### Claim 10 (depends on 5) An implant as in claim 5, wherein the lock comprises a clamp. ### Claim 11 (depends on 5) An implant as in claim 5, wherein the lock comprises a compression fit. ### Claim 12 (depends on 5) An implant as in claim 5, wherein the lock comprises a ratchet. ### Claim 13 (depends on 5) An implant as in claim 5, wherein the lock comprises an engagement surface, which is movable between a first, disengaged configuration and a second, engaged configuration. ### Claim 14 (depends on 5) An implant as in claim 5, wherein the lock is biased in a locked direction. ### Claim 15 (depends on 5) An implant as in claim 5, wherein the lock is biased in an unlocked direction. ### Claim 16 (depends on 5) An implant as in claim 5, further comprising a coating on the body. ### Claim 17 (depends on 1) An implant as in claim 1, further comprising an anchor for retaining the implant at a deployment site within a vessel. ### Claim 18 (depends on 17) An implant as in claim 17, wherein the anchor comprises a distal extension of the implant. ### Claim 19 (depends on 17) An implant as in claim 17, wherein the anchor comprises a friction enhancing surface structure for engaging the wall of the vessel. ### Claim 20 (depends on 17) An implant as in claim 17, wherein the anchor comprises at least one barb for piercing the wall of the vessel. ### Claim 21 (depends on 1) An implant as in claim 1, wherein the body has an axial length of no more than about 10 cm. ### Claim 22 (depends on 1) An implant as in claim 1, wherein the maximum cross sectional dimension through the implant is no more than about 10 mm. ### Claim 23 (depends on 1) An implant as in claim 1, further comprising an axially extending support in the body, attached to the forming element. ### Claim 24 (depends on 1) An implant as in claim 1, wherein the forming element comprises a metal wire. ### Claim 25 (depends on 1) An implant as in claim 1, wherein the forming element comprises a multifilament structure. ### Claim 26 (depends on 1) An implant as in claim 1, wherein the forming element comprises a screw thread. ### Claim 27 An implant for positioning within a vessel to influence tissue outside of the vessel, comprising: an elongate, flexible body, having a proximal end and a distal end, each of the proximal and distal ends dimensioned to reside completely within the vascular system; and a forming element attached within the body, the forming element comprising a screw, at least partially within the flexible body; wherein rotation of at least a portion of the forming element with respect to the body changes the shape of the body from an implantation configuration to a remodeling configuration, wherein at least a portion of the forming element remains attached to the body following implantation. ### Claim 28 (depends on 27) An implant as in claim 27, wherein the body is reversibly movable between an implantation configuration for transluminal implantation and a remodeling configuration for exerting a force against a vessel wall. ### Claim 29 (depends on 28) An implant as in claim 28, wherein the body defines an arc when in the remodeling configuration. ### Claim 30 (depends on 29) An implant as in claim 29, wherein a best fit constant radius curve corresponding to the arc has a radius within the range of from about 10 mm to about 20 mm. ### Claim 31 (depends on 27) An implant as in claim 27, further comprising a lock for retaining the body in the remodeling configuration. ### Claim 32 (depends on 31) An implant as in claim 31, wherein the lock comprises a locking ring. ### Claim 33 (depends on 31) An implant as in claim 31, wherein the lock comprises an interference fit. ### Claim 34 (depends on 31) An implant as in claim 31, wherein the lock comprises an adhesive bond. ### Claim 35 (depends on 31) An implant as in claim 31, wherein the lock comprises a suture knot. ### Claim 36 (depends on 31) An implant as in claim 31, wherein the lock comprises a clamp. ### Claim 37 (depends on 31) An implant as in claim 31, wherein the lock comprises a compression fit. ### Claim 38 (depends on 31) An implant as in claim 31, wherein the lock comprises a ratchet. ### Claim 39 (depends on 31) An implant as in claim 31, wherein the lock comprises an engagement surface, which is movable between a first, disengaged configuration and a second, engaged configuration. ### Claim 40 (depends on 31) An implant as in claim 31, wherein the lock is biased in a locked direction. ### Claim 41 (depends on 31) An implant as in claim 31, wherein the lock is biased in an unlocked direction. ### Claim 42 (depends on 31) An implant as in claim 31, further comprising a coating on the body. ### Claim 43 (depends on 27) An implant as in claim 27, further comprising an anchor for retaining the implant at a deployment site within a vessel. ### Claim 44 (depends on 43) An implant as in claim 43, wherein the anchor comprises a distal extension of the implant. ### Claim 45 (depends on 43) An implant as in claim 43, wherein the anchor comprises a friction enhancing surface structure for engaging the wall of the vessel. ### Claim 46 (depends on 43) An implant as in claim 43, wherein the anchor comprises at least one barb for piercing the wall of the vessel. ### Claim 47 (depends on 27) An implant as in claim 27, wherein the body has an axial length of no more than about 10 cm. ### Claim 48 (depends on 27) An implant as in claim 27, wherein the maximum cross sectional dimension through the implant is no more than about 10 mm. ### Claim 49 (depends on 27) An implant as in claim 27, further comprising an axially extending support in the body, attached to the forming element. ### Claim 50 (depends on 27) An implant as in claim 27, wherein the forming element comprises a polymeric strand. ### Claim 51 (depends on 27) An implant as in claim 27, wherein the forming element comprises a multifilament structure. ### Claim 52 An implant for positioning within a vessel to influence tissue outside of the vessel, comprising: an elongate, flexible body, having a proximal end and a distal end, each of the proximal and distal ends dimensioned to reside completely within the vascular system; and a forming element attached within the body, the forming element comprising a multifilament structure; wherein rotation of at least a portion of the forming element with respect to the body changes the shape of the body from an implantation configuration to a remodeling configuration, wherein at least a portion of the forming element remains attached to the body following implantation. ### Claim 53 (depends on 52) An implant as in claim 52, wherein the body is reversibly movable between an implantation configuration for transluminal implantation and a remodeling configuration for exerting a force against a vessel wall. ### Claim 54 (depends on 53) An implant as in claim 53, wherein the body defines an arc when in the remodeling configuration. ### Claim 55 (depends on 54) An implant as in claim 54, wherein a best fit constant radius curve corresponding to the arc has a radius within the range of from about 10 mm to about 20 mm. ### Claim 56 (depends on 52) An implant as in claim 52, further comprising a lock for retaining the body in the remodeling configuration. ### Claim 57 (depends on 56) An implant as in claim 56, wherein the lock comprises a locking ring. ### Claim 58 (depends on 56) An implant as in claim 56, wherein the lock comprises an interference fit. ### Claim 59 (depends on 56) An implant as in claim 56, wherein the lock comprises an adhesive bond. ### Claim 60 (depends on 56) An implant as in claim 56, wherein the lock comprises a suture knot. ### Claim 61 (depends on 56) An implant as in claim 56, wherein the lock comprises a clamp. ### Claim 62 (depends on 56) An implant as in claim 56, wherein the lock comprises a compression fit. ### Claim 63 (depends on 56) An implant as in claim 56, wherein the lock comprises a ratchet. ### Claim 64 (depends on 56) An implant as in claim 56, wherein the lock comprises an engagement surface, which is movable between a first, disengaged configuration and a second, engaged configuration. ### Claim 65 (depends on 56) An implant as in claim 56, wherein the lock is biased in a locked direction. ### Claim 66 (depends on 56) An implant as in claim 56, wherein the lock is biased in an unlocked direction. ### Claim 67 (depends on 56) An implant as in claim 56, further comprising a coating on the body. ### Claim 68 (depends on 52) An implant as in claim 52, further comprising an anchor for retaining the implant at a deployment site within a vessel. ### Claim 69 (depends on 68) An implant as in claim 68, wherein the anchor comprises a distal extension of the implant. ### Claim 70 (depends on 68) An implant as in claim 68, wherein the anchor comprises a friction enhancing surface structure for engaging the wall of the vessel. ### Claim 71 (depends on 68) An implant as in claim 68, wherein the anchor comprises at least one barb for piercing the wall of the vessel. ### Claim 72 (depends on 52) An implant as in claim 52, wherein the body has an axial length of no more than about 10 cm. ### Claim 73 (depends on 52) An implant as in claim 52, wherein the maximum cross sectional dimension through the implant is no more than about 10 mm. ### Claim 74 (depends on 52) An implant as in claim 52, further comprising an axially extending support in the body, attached to the forming element. ### Claim 75 (depends on 52) An implant as in claim 52, wherein the forming element comprises a polymeric strand. ### Claim 76 (depends on 52) An implant as in claim 52, wherein the forming element comprises a metal wire. ### Claim 77 (depends on 52) An implant as in claim 52, wherein the forming element comprises a screw thread.