Electrotransort device comprising blades
AssigneeJohnson & Johnson Consumer Companies, Inc.
InventorsYing Sun, Ralph W. Oakeson, Stephen J. Wisniewski, Jonas C. T. Wang, Susan M. Niemiec
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Abstract
The present invention relates to an apparatus for transporting a compound through a barrier membrane of a mammal comprising: (a) a vessel having a membrane contacting surface, said surface having a plurality of exposed blades and a channel adjacent to said blades; (b) a reservoir in communication with said channels for storage of said compound; and (c) an electrode in communication with said reservoir, wherein the width of said blades are tapered away from said surface.
Claims20
An apparatus for transporting a compound through a barrier membrane of a mammal comprising:
- (a) a vessel having a membrane contacting surface, said surface having a plurality of exposed blades and a channel adjacent to said blades;
- (b) a reservoir in communication with said channels for storage of said compound;
- and
- (c) an electrode in communication with said reservoir,
- wherein the width and the thickness of said blades are tapered away from said surface.
A transdermal iontophoretic system comprising:
- (a) a first electrode comprising
- (1) a vessel having a membrane contacting surface, said membrane contacting surface having a plurality of exposed blades and channels adjacent said blades wherein the width and the thickness of said blades are tapered away from said surface;
- (2) a reservoir in communication with said channels;
- and
- (3) an electrode in communication with said reservoir;
- (b) a counter electrode;
- and
- (c) an electronic control unit,
- wherein said electronic control unit is electrically connected to said electrode and said counter electrode, and said electronic control unit controls the electrical current through said electrode.
A method for transporting a compound across a barrier membrane of a mammal comprising:
- (a) penetrating said barrier membrane with a plurality of blades spaced at predetermined intervals to form pathways through said barrier membrane;
- and
- (b) applying an electrical current through said mammal to cause a compound to cross said barrier membrane through said pathways,
- wherein the width and the thickness of said blades are tapered away from said surface.
Dependencies are inferred from the claim text.