Immunosuppressive agents
AssigneeQiang Xu
InventorsQiang Xu, Ikuo Saiki, Ting Chen, Katsuko Komatsu
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Abstract
An immunosuppressive agent which is very effective for treating autoimmune disease, inflammatory reaction, fibrosis or dysfunction caused by autoimmune disease and related disease thereof with tissue injury or infection, rejection of transplantation, graft versus host disease by bone marrow (hematopoietic stem cell) transplantation, or allergic disease, by selectively inhibiting the activated T cells, is provided.
Claims7
A method for treating diseases due to abnormal immune response induced by activated T cells comprising administering an effective amount of an immunosuppressive agent having a selective inhibitory activity against activated T cells,
- wherein said agent comprises flavanoids or chromones represented by the following formula (I):
- wherein,
- R is a hydrogen atom or a phenyl group which may be substituted with one or two hydroxy groups,
- Rha is an O-L-rhamnose residue, and
- the dotted line indicates with or without a double bond, as an active ingredient.
Dependencies are inferred from the claim text.