Compositions of flavonoids for use as cytoprotectants and methods of making and using them
AssigneeGalileo Laboratories, Inc.
InventorsLesley A. Brown, Guy Miller
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Abstract
Non-naturally-occurring compositions for use in amelioration of disruption of energy metabolism secondary to stress are described. These compositions comprise a flavonoid or derivative thereof and a synergist. Synergists include, but are not limited to, amino acids, carbohydrates, carnitines, flavonoids, nucleosides, and tocopherols and/or derivatives thereof. Methods of making these compositions and methods of ameliorating disruption of energy metabolism secondary to stress, comprising administering such synergistic compositions, are also disclosed.
Claims22
A non-naturally-occurring nutritional composition for amelioration of disruption of energy metabolism in cells secondary to stress in a subject in need thereof, comprising a flavonoid, or derivative thereof, and a synergist, wherein the synergist is selected from the group consisting of amino acids, carbohydrates, carnitines, and nucleosides and derivatives thereof, and wherein the flavonoid and the synergist are present in amounts effective to ameliorate said disruption of energy metabolism secondary to strees in said cells.
A non-naturally-occurring nutritional composition for amelioration of disruption of energy metabolism in cells secondary to stress in a subject of need thereof, comprising a first flavonoid, or derivative thereof, and a second flavonoid synergist, wherein the first flavonoid and the second flavonoid are different, and wherein the first flavonoid and the second flavonoid are present in amounts effective to ameliorate said disruption of energy metabolism secondary to stress in said cells.
Dependencies are inferred from the claim text.