Transdermal therapeutic system containing estradiol
AssigneesLTS Lohmann Therapie-Systeme AG, Merck Patent GmbH
InventorsReinhold Meconi, Frank Seibertz, Michael Horstmann, Rainer Lichtenberger
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Abstract
An active-substance-containing transdermal therapeutic system for the controlled release of estradiol or its pharmaceutically acceptable able derivatives alone or combined with gestagens consisting of a layer, an active-substance-containing reservoir which is bonded thereto and produced by using pressure sensitive adhesives, and a removable protective layer is characterized by the fact that the pressure sensitive adhesive comprises esters of colophony.
Claims24
A transdermal therapeutic system for the controlled release of estradiol or a pharmaceutically acceptable derivative thereof, said system comprising a backing layer;
- an active-substance-containing reservoir which is bonded to the backing layer and which comprises pressure sensitive adhesive and estradiol or a pharmaceutically acceptable derivative thereof combined with a gestagen;
- and a removable protective layer, wherein the pressure sensitive adhesive comprises
- (a) a styrene-isoprene block copolymer, and
- (b) a hydrogenated resin acid or its derivatives in an amount of 55-92% wt.
Dependencies are inferred from the claim text.