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US 6,521,223 B1Granted
Single phase gels for the prevention of adhesions
AssigneeGenzyme Corporation
InventorsPericles Calias, Robert J. Miller
Life of this patent
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Abstract
Single phase gels for preventing the formation of surgical adhesions are disclosed. The gels are prepared by reacting an aqueous solution of a polyanionic polysaccharide, such as hyaluronic acid or carboxymethyl cellulose, with divinyl sulfone, to form a gel, the solution is neutralized, and a solid is precipitated from the solution. The solid can be redissolved in water to form a gel having properties which can be modified to suit a particular application.
Claims15
A method for preparing a water insoluble biocompatible composition comprising
- reacting a polyanionic polysaccharide with divinyl sulfone in an aqueous solution to form a gel, neutralizing the pH of the solution, and precipitating a solid from the neutral solution.
Dependencies are inferred from the claim text.