Fluidic device for medical diagnostics
AssigneeLifeScan, Inc.
InventorsRobert Justice Shartle, Herbert Chow, Christa Hartmann
Life of this patent
Estimating the term…
Abstract
A fluidic medical diagnostic device permits measurement of analyte concentration or a property of a biological fluid, particularly the coagulation time of blood. The device has at one end a sample port for introducing a sample and at the other end a bladder for drawing the sample to a measurement area. A channel carries the sample from the sample port to the measurement area, and a stop junction, between the measurement area and bladder, halts the sample flow. The desired measurement can be made by placing the device into a meter which measures a physical property of the sample—typically, optical transmittance—after it has interacted with a reagent in the measurement area.
Claims21
A fluidic diagnostic device for measuring an analyte concentration or property of a biological fluid, comprising:
- a first layer and second layer, at least one of which has a resilient region over at least a part of its area, separated by an intermediate layer, in which cutouts in the intermediate layer form, with the first and second layers,
- a sample port for introducing a sample of the biological fluid into the device;
- a first measurement area, in which a physical parameter of the sample is measured and related to the analyte concentration or property of the fluid;
- a first channel, having a first end and a second end, to provide a fluidic path from the sample port at the first end through the first measurement area;
- a first bladder, at the second end of the first channel, comprising at least a part of the resilient region in at least the first or second layer and having a volume that is at least about equal to the combined volume of the first measurement area and first channel;
- and
- a first stop junction in the first channel between the first measurement area and first bladder that further comprises a co-aligned through hole in the first or second layer, the through hole overlaid with a third layer, wherein fluid flowing into the stop junction is stopped.
A fluidic diagnostic device for measuring an analyte concentration or property of a biological fluid, comprising:
- a first layer, which has a resilient region over at least a part of its area, and a second layer, separated by an intermediate layer, in which recesses in a first surface of the intermediate layer form, with the first layer,
- a sample port for introducing a sample of the biological fluid into the device;
- a measurement area, in which the sample undergoes a change in a physical property that is measured and related to the analyte concentration or property of the fluid;
- a channel, having a first end and a second end, to provide a fluidic path from the sample port at the first end through the first measurement area;
- a bladder, at the second end of the first channel, comprising the resilient region in the first layer and having a volume that is at least about equal to the combined volume of the measurement area and channel;
- and
- a stop junction in the channel between the measurement area and bladder that comprises two passages substantially normal to the first surface of the intermediate layer, each passage having a first end in fluid communication with the channel and a second end in fluid communication with a recess in a second surface of the intermediate layer, which recess provides fluid communication between the second ends of the passages, wherein fluid flowing into the stop junction is stopped.
Dependencies are inferred from the claim text.