Method and apparatus for selectively targeting specific cells within a cell population
AssigneeOncosis LLC
InventorsBernhard O. Palsson, Manfred R. Koller, Timothy M. Eisfeld
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Abstract
This invention provides a method and apparatus for selectively identifying, and targeting with an energy beam, specific cells within a cell population, for the purpose of inducing a response in the targeted cells. Using the present invention, every detectable cell in a population can be identified and affected, without substantially affecting non-targeted cells within the mixture.
Claims20
A method for selectively inducing a response in one or more targeted cells within a biological specimen, comprising:
- illuminating a frame of cells within a field-of-view in said biological specimen, wherein said field-of-view comprises a plurality of frames of cells;
- capturing an image of said frame of cells;
- determining the locations of said one or more targeted cells within said image;
- and
- steering an energy beam to the locations of said one or more targeted cells, wherein said energy beam is sufficient to induce a response in at least one of said one or more targeted cells.
A method for rapidly inducing a response in individual cells within a cell population, said cell population being held in a container, comprising:
- illuminating a first frame of cells in a first field-of-view in said cell population;
- wherein said field of view comprises a plurality of frames of cells;
- capturing an image of said first frame of cells within said first field-of-view;
- determining the locations of first individual cells within said first frame of cells by reference to said image;
- and
- steering an energy beam to the locations of said first individual cells, wherein said energy beam is sufficient to induce a response in at least one of said first individual cells.
A method for selectively inducing a response in one or more targeted cells within a biological specimen, comprising:
- focusing a scanning lens on a field-of-view within said biological specimen, said field-of-view comprising a plurality of frames of cells;
- illuminating one or more frames of cells within said field-of-view;
- capturing an image of a first frame of cells in said field-of-view;
- determining the locations of said one or more targeted cells in said first frame of cells;
- emitting an energy beam sufficient to induce a response in at least one of said one or more targeted cells;
- and
- steering said energy beam to the locations of said one or more targeted cells within said first frame of cells.
Dependencies are inferred from the claim text.