Osteoinductive ceramic materials
AssigneeIsoTis N.V.
InventorsJoost D. de Bruijn, Klaas de Groot, Clemens A. van Blitterswijk, Yuan Huipin
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Abstract
The invention relates to an osteoinductive biomaterial, which is based on a ceramic material and which has a total porosity of 20 to 90%, wherein macropores are present having a size ranging from 0.1 to 1.5 mm, and wherein micropores are present having a size ranging from 0.05 to 20 μm. The invention further relates to a process for preparing said osteoinductive biomaterial.
Claims7
A method of inducing bone formation in a mammal comprising implanting an osteoinductive biomaterial into a mammal in a manner to induce bone formation on the osteoinductive biomaterial, wherein the osteoinductive biomaterial comprises a ceramic material having a total porosity of between 20% to 90% and a microporosity of the material's surface of between 40% to 60%, and comprises crystals having a crystal size of between 0.05 μm to 20 μm, and wherein the ceramic material comprises macropores having a size ranging from 0.1 mm to 1.5 mm, and micropores in the surface of the macropores, wherein the micropores have a size ranging from 0.05 μm to 20 μm.
Dependencies are inferred from the claim text.