Valve for aerosol container
AssigneeSmithKline Beecham Corporation
InventorsPatrick Di Giovanni, Cheryl Vanessa Rogerson
Life of this patent
Estimating the term…
Abstract
Valve for an aerosol container for dispensing a suspension of a substance in a liquid propellant contained therein. The valve comprises a valve body (1) having at least one orifice (16) to allow a quantity of the suspension to pass from the container into the valve. The valve further comprises a ring (18) disposed around the valve body (1), the ring being positioned below the at least one orifice to reduce the volume of suspension that can be accommodated within the container below the at least one orifice when the container is orientated with the valve at the bottom, the ring having at least one portion of reduced axial thickness to provide a trough (19) around the valve body below the at least one orifice.
Claims22
A drug product comprising:
- an aerosol container containing a suspension of drug particles in a liquid propellant in communication with
- a metering valve comprising:
- a valve body;
- a metering chamber;
- a valve stem;
- one or more stem seals;
- and,
- at least one orifice in the valve body;
- and,
- a ring having a trough disposed around the valve body,
- wherein the ring further includes an annular wall interrupted with a plurality of slots forming a plurality of vanes, wherein, upon shaking of the valve, the suspension flows around the plurality of vanes assisting in dispersion of drug particles in the suspension;
- wherein the metering valve is suitable for dispensing the suspension of drug particles in the liquid propellant, and,
- wherein the drug is a member selected from the group consisting of salmeterol, salbutamol, formoterol, ipratropium, fluticasone, beclomethasone, budesonide, terbutaline, salts, esters and solvates thereof, and combinations thereof.
A drug product comprising:
- a means for containing a suspension of drug particles in a liquid propellant in communication with
- a means for metering the suspension;
- and,
- a means for assisting in dispersion of the suspension;
- wherein the metering means is suitable for dispensing the suspension of drug particles in the liquid propellant, and,
- wherein the drug is a member selected from the group consisting of salmeterol, salbutamol, formoterol, ipratropium, fluticasone, beclomethasone, budesonide, terbutaline, salts, esters and solvates thereof, and combinations thereof.
A drug product comprising:
- an aerosol container containing a suspension of drug particles in a liquid propellant in communication with
- a metering valve comprising:
- a valve body;
- at least one orifice,
- a sampling chamber having an axial length,
- a metering chamber,
- a transfer passage between the sampling chamber and the metering chamber,
- a valve stem,
- one or more stem seals;
- and,
- a dispensing passage within the valve stem, and,
- a ring having a trough and an annular wall interrupted with a plurality of slots and a plurality of vanes, the ring disposed around the valve body,
- wherein the valve stem is slideably moveable within the valve body such that in a first position the dispensing passage is isolated from the metering chamber and the metering chamber is in communication with the sampling chamber via the transfer passage,
- wherein the valve stem is slideably moveable within the valve body such that in a second position the dispensing passage is in communication with the metering chamber and the transfer passage is isolated from the metering chamber,
- wherein the metering valve is suitable for dispensing the suspension of drug particles in the liquid propellant, and
- wherein the drug is a member selected from the group consisting of salmeterol, salbutamol, formoterol, ipratropium, fluticasone, beclomethasone, budesonide, terbutaline, salts, esters and solvates thereof, and combinations thereof.
Dependencies are inferred from the claim text.