Tracking apparatus and method for use with combinatorial synthesis processes
AssigneeRobert D. Frankel
InventorRobert D. Frankel
Life of this patent
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Abstract
A combinatorial chemistry bead that includes an electromagnetic spectral emitter that radiates a distinct electromagnetic code for each bead that uniquely identifies each bead, a terminal apparatus for receiving the electromagnetic code from each bead, and a method for performing combinatorial synthesis using a bead that transmits a distinct electromagnetic code. The invention includes a large number of spectrally narrowed light emitting mechanisms for generating distinct optical codes.
Claims26
A mobile transport bead for use in identifing an oligomeric compound in a combinatorial synthesis process, the mobile transport bead comprising:
- at least one growth matrix region;
- at least one molecular anchoring site attached to said at least one growth matrix region;
- and
- an electromagnetic spectrum emitter coupled to the at least one growth matrix region, the electromagnetic spectrum emitter including a plurality of scattering gain medium laser elements, each scattering gain medium laser element of the plurality of scattering gain medium laser elements being operative to transmit an electomagnetic emission at a predetermined frequency, such that a plurality of electromagnetic emissions are transmitted by the electromagnetic spectrum emitter, the plurality of electromagnetic emissions being characterized by a unique ensemble of predetermined frequencies, whereby the unique ensemble of predetermined frequencies serves as an identification code for the mobile transport bead.
An apparatus for use in identifying an oligomeric compound in a combinatorial synthesis process, the apparatus comprising:
- at least one mobile transport bead, the at least one mobile transport bead including at least one growth matrix having at least one molecular anchoring site attached thereto, the at least one mobile transport bead also including an electromagnetic spectrum emitter including a plurality of scattering gain medium laser elements, each scattering gain medium laser element of the plurality of scattering gain medium laser elements being operative to transmit an electromagnetic emission at a predetermined frequency, such that a plurality of electromagnetic emissions are transmitted by the electromagnetic spectrum emitter, the plurality of electromagnetic emissions being characterized by a unique ensemble of predetermined frequencies, whereby the unique ensemble of predetermined frequencies serves as an identification code for the at least one mobile transport bead;
- and
- a terminal apparatus including a detector operative to convert the plurality of electromagnetic emissions into electrical signals, and a computer operative to decode the electical signals to thereby obtain the identification code of the at least one mobile transport bead, and associate the identification code with a corresponding combinatorial synthesis process.
A system for use in identifying an oligomeric compound in a combinatorial synthesis process, the system comprising:
- a plurality of mobile transport beads, each mobile transport bead including,
- at least one growth matrix region;
- at least one molecular anchoring site attached to said at least one growth matrix region;
- and
- an electromagnetic spectrum emitter coupled to the at least one growth matrix region, the electromagnetic spectrum emitter including at least one scattering gain medium laser, the at least one scattering gain medium laser being operative to transmit an electromagnetic emission having at least one frequency of a plurality of predetermined frequencies, whereby the at least one frequency serves as an identification code that uniquely identifies each mobile transport bead within the plurality of mobile transport beads.
Dependencies are inferred from the claim text.