Bioresorbable oxidized cellulose composite material for prevention of postsurgical adhesions
AssigneeEthicon, Inc.
InventorsDavid M. Wiseman, Lowell Saferstein, Stephen Wolf
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Abstract
An improved adhesion-preventative physical barrier, wound dressing and drug delivery system comprising an oxidized cellulose film made up of multiple layers of a cellulose fabric or like material and a cellulose film. A method for forming an improved oxidized cellulose film and for using the same to prevent the formation of postsurgical adhesions and/or to dress a wound and/or to deliver one or more drugs.
Claims23
A method for forming an oxidized cellulose multi-layered bioresorbable film for use as an adhesion-preventative barrier, comprising the steps of:
- spreading a cellulose film onto a surface;
- combining at least one layer of a cellulose fabric material with said cellulose film with an adhesive material capable of oxidation to form a bioresorbable material to form a multi-layered film;
- oxidizing the multi-layered film;
- and
- sterilizing the multi-layered film.
A method for forming an oxidized cellulose multi-layered bioresorbable film for use as an adhesion-preventative barrier, comprising the steps of:
- spreading a cellulose film onto a surface;
- combining at least one layer of a cellulose fabric material with said cellulose film using an oxidizable carbohydrate adhesive material capable of oxidation to produce a bioresorbable material to form a multi-layered film;
- oxidizing the multi-layered film in the presence of nitrogen dioxide for between 4 and 48 hours at a temperature of between 20° C. and 35° C. and a pressure of between 1 and 5 atmospheres;
- and
- sterilizing the multi-layered film.
Dependencies are inferred from the claim text.