Compositions which contain at least one cationic polymer and at least one active molecule contained in at least one micro or nonopartculate vector, and their use for treating living or inert surfaces
AssigneeVirbac
InventorsGuy Derrieu, Jean-Luc Pougnas, Patricia Monginoux, Christian Karst
Life of this patent
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Abstract
The present invention relates to compositions which contain at least one cationic polymer and at least one active molecule contained in at least one micro or nanoparticulate vector, and their use for treating living or inert surfaces.
Claims17
A composition for skin treatment, comprising:
- a) a pharmaceutically or cosmetically acceptable medium
- b) dispersed directly within the medium, 0.001 to 5% by weight of the composition of at least one cationic polymer selected from the group consisting of cationic polysaccharides;
- and
- c) dispersed within the medium, 0.5 to 50% by weight of the composition of microparticles or nanoparticles containing at least one biologically active molecule therein selected from the group consisting of an antiseptic, an antibiotic, an antiviral, an antifungal, an antiparasitic, an insecticidal, an acaricidal and an antimitotic for treating the skin, said microparticles or nanoparticles being approximately spherical multilamellar vesicles of onion structure,
- whereby the combination of the at least one cationic polymer and the microparticles or nanoparticles improves the activity of the at least one active molecule.
A method for improving activity of at least one biologically active substance selected from the group consisting of an antiseptic agent, an antibiotic agent, an antiviral agent, an antifungal agent, an antiparasitic agent, an insecticidal agent, an acaricidal agent and an antimitotic agent by increasing its activity and duration thereof which comprises combining, within a pharmaceutically or cosmetically acceptable medium said at least one said active substance contained in microparticles or nanoparticles which are approximately spherical multilamellar vesicles of onion structure, and at least one cationic polymer selected from the group consisting of cationic polysaccharides, the at least one cationic polymer being dispersed directly within the medium.
A composition for skin treatment, comprising:
- a) a pharmaceutically or cosmetically acceptable medium;
- b) dispersed directly within the medium, 0.001 to 5% by weight of the composition of at least one cationic polymer selected from the group consisting of cationic polysaccharides;
- and
- c) dispersed within the medium, 0.5 to 50% by weight of the composition of microparticles or nanoparticles containing at least one biologically active molecule therein selected from the group consisting of an antiseptic, an antibiotic, an antiviral, an antifungal, an antiparasitic, an insecticidal, an acaricidal and an antimitotic for treating the skin, said microparticles or nanoparticles being approximately spherical multilamellar vesicles of onion structure,
- whereby the simultaneous presence of the at least one cationic polymer and the microparticles or nanoparticles in said composition improves the activity of the at least one active molecule by reducing time required for a desired antiseptic, antibiotic, antiviral, antifungal, antiparasitic, insecticidal, acaricidal, or antimiotic activity in comparison to a composition in which either the microparticles or nanoparticles of the cationic polymer, or both, are not present.
A composition for skin treatment, comprising:
- a) a pharmaceutically or cosmetically acceptable medium;
- b) dispersed directly within the medium, 0.001 to 5% by weight of the composition of at least one cationic polymer selected from the group consisting of cationic polysaccharides;
- and
- c) dispersed within the medium, 0.5 to 50% by weight of the composition of microparticles or nanoparticles containing at least one biologically active molecule therein selected from the group consisting of an antiseptic, an antibiotic, an antiviral, an antifungal, an antiparasitic, an insecticidal, an acaricidal and an antimitotic for treating the skin, said microparticles or nanoparticles being approximately spherical multilamellar vesicles of onion structure,
- whereby the simultaneous presence of the at least one cationic polymer and the microparticles or nanoparticles in said composition improves the activity of the at least one active molecule by increasing duration of a desired antiseptic, antibiotic, antiviral, antifungal, antiparasitic, insecticidal, acaricidal, or antimiotic activity in comparison to a composition in which either the microparticles or nanoparticles of the cationic polymer, or both, are not present.
Dependencies are inferred from the claim text.