Porcine circovirus recombinant poxvirus vaccine
AssigneeMerial Limited
InventorsMichel Bublot, Jennifer M. Perez, Catherine E. Charreyre
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Abstract
What is described is a recombinant poxvirus, such as avipox virus, containing foreign DNA from porcine circovirus 2. What are also described are immunological compositions containing the recombinant poxvirus for inducing an immunological response in a host animal to which the immunological composition is administered. Also described are methods of treating or preventing disease caused by porcine circovirus 2 by administering the immunological compositions of the invention to an animal in need of treatment or susceptible to infection by porcine circovirus 2.
Claims26
A recombinant poxvirus comprising an isolated DNA molecule selected from the group consisting of ORFs 1 to 13 of porcine circovirus type II, wherein the poxvirus is:
- ALVA C, or
- a poxvirus having all the identifying characteristics of ALVAC.
An immunological composition comprising a recombinant avipox virus comprising an isolated DNA molecule selected from the group consisting of ORFs 1 to 13 of porcine circovirus type II, and a carbomer adjuvant.
A recombinant avipox virus comprising an isolated DNA molecule comprising porcine circovirus type II (PCV2) open reading frames 1 and 2 (ORFs 1 and 2).
Dependencies are inferred from the claim text.