Microfabricated devices for the delivery of molecules into a carrier fluid

An apparatus for delivery of a drug into a carrier fluid for subsequent administration to a patient comprising

• (i) a microchip device having a plurality of reservoirs containing the molecules for release, and
• (ii) a mixing chamber,
• wherein the molecules are combined with the carrier fluid in the mixing chamber following release of the molecules from the reservoir.

A device for the release of molecules in vivo comprising

• a medical stent, and
• a microchip device having a plurality of reservoirs containing the molecules for release,
• wherein the microchip device is integrated into or is attached to a surface of the medical stent.

A device for the release of drug molecules in vivo comprising

• a medical stent having a plurality of microfabricated reservoirs containing the molecules for release.

A device for the controlled delivery of molecules comprising

• (i) a microchip device having a plurality of reservoirs containing the molecules and sealed by reservoir caps, and
• (ii) an implanted delivery system comprising a pump,
• wherein the reservoirs of the microchip device are selectively exposed to the flow of fluid, in vivo, in the delivery system, and wherein the molecules are released from the reservoirs, upon disintegration of the reservoir caps, during fluid flow in the delivery system.