Microfluidic devices and systems incorporating cover layers
AssigneeCaliper Technologies Corp.
InventorsRobert S. Dubrow, Colin B. Kennedy, Robert Nagle
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Abstract
The present invention provides microfluidic devices that comprise a body structure comprising at least a first microscale channel network disposed therein. The body structure has a plurality of ports disposed in the body structure, where each port is in fluid communication with one or more channels in the first channel network. The devices also include a cover layer comprising a plurality of apertures disposed through the cover layer. The cover layer is mated with the body structure whereby each of the apertures is aligned with a separate one of the plurality of ports.
Claims10
A microfluidic apparatus, comprising:
- a device comprising a body structure, wherein disposed within said body structure is at least one microscale channel network, said microscale channel network in fluid communication with at least one reservoir;
- said at least one reservoir comprising a rim disposed circumferentially around it, said rim and a portion of an internal surface of said reservoir comprising a conductive coating;
- a cover layer mated with said device, wherein said cover layer comprises at least one aperture, said at least one aperture aligned with said at least one reservoir;
- and
- at least one semi-permeable membrane portion, said membrane portion disposed over said at least one aperture.
The apparatus of claim wherein the at least one semi-permeable membrane portion comprises a pore size of between about 10 μm and about 100 μm.
Dependencies are inferred from the claim text.