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US 6,488,894 B1Granted
Device for sequential discharge of flowable reagents
AssigneeBiognosis GmbH
InventorsPeter Miethe, Dimitri Plaksine, Elena Gromakovskaja
Life of this patent
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Abstract
The invention relates to a device in which at least two liquid or semi-liquid reagents can be stored separately. When used, the inventive device enables precise, chronologically defined, sequential reagent discharge in a reaction chamber by means of a linear movement without any prior mixing of said reagents.
Claims12
A device for sequentially discharging flowable reagents, comprising:
- a receptacle comprising a receiving chamber with two opposite ends, the receptacle having a relief opening at the first end of the receiving chamber,
- a pressure generating unit adapted to be positioned or arranged at the receptacle at the second end of the receiving chamber, and adapted to build pressure in the receiving chamber,
- a reagent column contained in the receiving chamber, comprising at least two reagent volumes separated by a respective partition element, each partition element abutting the inside of the receptacle in a sealing manner and being slidable into the receiving chamber towards the first end thereof,
- an outlet opening arranged at a branch between the first and the second end of the receiving chamber, the distance between the outlet opening and the relief opening being at least as great as the thickness of the first partition element between the outlet opening and the second end of the receiving chamber,
- a holding force generating unit arranged in the region between the outlet opening and the relief opening in the receiving chamber, for generating a holding force acting at least on the partition elements within this region of the receiving chamber, which is great enough to cause a high flow resistance to the reagents in this region that is higher than the resistance occurring when the reagents flow out from the outlet opening.
2 more elements
Dependencies are inferred from the claim text.