Thin film fiber optic electrode sensor array and apparatus
AssigneeBoard of Regents, The University of Texas System
InventorsPaul Pantano, Eunsook S. Jin, Samina S. Khan, Harold W. Stokes, Jr.
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Abstract
An apparatus and method is disclosed for detecting an analyte using a fiber optic electrochemical sensor that includes a fiber optic layer, an electrically conductive translucent metallic layer and a light energy absorbing dye layer.
Claims22
A sensor probe for detecting an analyte comprising:
- a fiber optic layer;
- an electrically conductive translucent metallic layer disposed on the fiber optic layer;
- and
- a light energy absorbing dye disposed on the metallic layer.
A fiber optic electrochemical sensor for detecting an analyte comprising:
- a fiber optic bundle having a first and a second end;
- an electrically conductive translucent metallic layer disposed on the first end of the fiber optic bundle;
- and
- a light energy absorbing dye layer disposed on the metallic layer.
A fiber optic electrochemical sensor for detecting an analyte comprising:
- a fiber optic bundle comprised of individual optic fibers wherein each individual optic fiber has a diameter of less than 10 micrometers and wherein the bundle has a diameter of less than 2 millimeters having first and second ends;
- an electrically conductive translucent metallic layer disposed on the first end of the fiber optic bundle;
- and
- a light energy absorbing dye layer disposed on the metallic layer,
- wherein the fiber optic electrochemical sensor is capable of electrochemical regeneration of the light absorbing dye layer.
A fluorescence based imaging fiber electrode chemical sensor system comprising:
- a fiber optic electrochemical sensor;
- a potentiomer in electric communication with the fiber optic electrochemical sensor;
- a microscope including a light source and an objective in optic communication with the fiber optic electrochemical sensor wherein the objective communicates light from the source to the fiber optic electrochemical sensor and receives light returning from the sensor;
- and
- a means for recording light returning from the sensor though the objective.
A method for preparing a imaging fiber electrode comprising the steps of:
- polishing a face of the fiber optic bundle;
- silanizing the face using a trimethyoxysilane;
- and
- sputter coating the silanized face to deposit a 10-30 nm thick semi-transparent metal layer.
A method for preparing a imaging fiber chemical sensor comprising the steps of:
- obtaining a fiber optic electrode having a 15-30 nm gold film on a distal end and an electrically conductive aspect leading from the distal end and along a lateral dimension of the fiber optic electrode;
- coating the fiber optic electrode with an ion-exchange polymer;
- and
- applying a luminescent reporter group.
Dependencies are inferred from the claim text.