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US 6,486,329 B1Granted
Amorphous form of cell cycle inhibitor having improved solubility and bioavailability
AssigneeHoffmann-La Roche Inc.
InventorsAntonio A. Albano, Wantanee Phuapradit, Harpreet K. Sandhu, Navnit Hargovindas Shah
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Abstract
The present invention provides a method for preparing an amorphous, pharmaceutically active form of a compound of formula I which is substantially free of crystalline compound.
Claims4
A method of making a compound of formula I
- in amorphous form substantially free of crystalline compound and not dispersed in an ionic polymer comprising:
- (a) dissolving a compound of formula I in crystalline form in an organic solvent;
- and
- (b) removing the organic solvent.
1 more element
Dependencies are inferred from the claim text.