Single pot process for preparing metal picolinates from alpha picoline
AssigneeJubilant Organosys Limited
InventorsVerma Pradeep Kumar, Agarwal Ashutosh, Bhardwaj Nikhlesha Chandra, Singh Samir Kumar
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Abstract
The present invention relates to a single pot process for the preparation of metal picolinates useful as dietary supplement from alpha picoline, said process comprising hydrosulphonation of alpha picoline with sulphuric acid; heating the reaction mixture thus obtained between the range of 150° to 210° C. followed by oxidation with any suitable oxidizing agent to obtain alpha picolinic acid sulphate, and treating the thus obtained alpha picolinic acid sulphate with a metal salt solution to obtain corresponding metal picolinate.
Claims22
A single pot process for the preparation of zinc and/or chromium picolinates useful as dietary supplements from alpha picoline, said process comprising the steps of:
- (a) hydrosulfonation of alpha picoline with sulfuric acid at a temperature of about 35-100° C. to form a reaction mixture;
- (b) further heating the reaction mixture thus obtained to a temperature of about 150°-210° C.;
- (c) oxidizing the reaction mixture of step (b) with an oxidizing agent to obtain alpha picolinic acid sulfate at a temperature of about 50-90° C. to form a solution;
- (d) maintaining the pH of the solution of step (c) at a pH of about 3 to 5 as an acidic solution;
- (e) treating the acidic solution of step (d) with a water soluble zinc and/or chromium salt to produce a solid metal picolinate in said water;
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- (f) filtering the resulting solid metal picolinate to remove such from said water and to thereby obtain the corresponding metal picolinates of high purity.
Dependencies are inferred from the claim text.