Compounds and methods for the treatment of post traumatic stress disorder

A method for treating a mammalian patient comprising determining that the patient suffers from post traumatic stress disorder, and then administering to the patient a therapeutically effective amount of a compound of the formula I:

• wherein
• X is CH2 or oxygen;
• R1 is hydrogen or alkyl;
• and
• R2, R3, R4 and R5 are independently hydrogen or lower alkyl and, when X is CH2, R4 and R5 may be alkene groups joined to form a benezene ring and, when X is oxygen, R2 and R3 and/or R4 and R5 together may be a methylenedioxy group of the following formula (II):
• wherein R6 and R7 are the same or different and are hydrogen, lower alkyl or are alkyl and are joined to form a cyclopentyl or cyclohexyl ring;
• or a pharmacologically acceptable acid addition salt thereof, alone or in association with a pharmaceutically acceptable carrier.