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US 6,486,195 B1Granted
Thermodynamically stable crystal form of 4″-deoxy-4″-epi-methylamino avermectin B1a/B1b benzoic acid salt and processes for its preparation
AssigneeMerck & Co., Inc.
InventorsRaymond Cvetovich, James A. McCauley, Richard Demchak, Richard J. Varsolona
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Abstract
The most thermodynamically stable crystalline form of the benzoic acid salt of 4″-deoxy-4″-epi-methylamino avermectin B1a/B1b as the hemihydrate is obtained by crystallization from organic solvents containing a controlled amount of water.
Claims4
A crystalline compound 4″-deoxy-4″-epi-methylamino avermectin B1a/B1b, benzoic acid salt, hemihydrate Type B in substantially pure form.
Dependencies are inferred from the claim text.