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US 6,486,155 B1Granted
Method of inhibiting neoplastic cells with isoquinoline derivatives
AssigneeCell Pathways, Inc.
InventorsRifat Pamukcu, Gary A. Piazza
Life of this patent
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Abstract
A method for inhibiting neoplasia, particularly cancerous and precancerous lesions by exposing the affected cells to isoquinoline derivatives.
Claims2
A method of treating a mammal having precancerous lesions sensitive to a compound below comprising administering a pharmacologically effective amount of a compound of Formula I or pharmaceutically acceptable salt thereof:
- wherein
- Ring A and Ring B are the same or different and each a substituted or unsubstituted benzene ring, R1 is morpholine, R2 is —COOR3, and R3 is alkyl.
A method for inhibiting the growth of neoplastic cells sensitive to a compound below comprising exposing the cells to a growth inhibiting effective amount of a compound of Formula I or pharmaceutically acceptable salt thereof:
- wherein
- Ring A and Ring B are the same or different and each a substituted or unsubstituted benzene ring, R1 is morpholine, R2 is —COOR3, and R3 is alkyl.
Dependencies are inferred from the claim text.