Reagent test strip for analyte determination having hemolyzing agent
AssigneeLifeScan, Inc.
InventorsAdva Yani, Paing C. Huang
Life of this patent
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Abstract
Reagent test strips and methods for their use in the determination of the concentration of an analyte, e.g. glucose, in a physiological sample, are provided. The subject reagent test strips include one or more members of an analyte oxidation signal producing system and at least one hemolyzing agent. The subject reagent test strips and methods are particularly suited for use in the detection of blood glucose concentrations. Also provided are kits that include the subject test strips for use in practicing the subject methods.
Claims16
A reagent test strip for use in determining analyte concentration in a physiological sample, said strip comprising:
- a porous matrix;
- at least one member of an analyte oxidation signal producing system;
- and
- at least one hemolyzing agent, wherein said hemolyzing agent is present in an amount sufficient to produce hemolysis which is equivalent to hemolysate concentration in a physiological sample applied to said porous matrix in an amount ranging from about 5 to 20% by volume.
A reagent test strip for use in determining blood glucose concentration, said test strip comprising:
- a porous matrix;
- a glucose oxidation based signal producing system;
- and
- at least one hemolyzing agent, wherein said hemolyzing agent is present in an amount sufficient to produce hemolysis which is equivalent to hemolysate concentration in a physiological sample applied to said porous matrix in an amount ranging from about 5 to 20% by volume.
A reagent test strip for use in determining blood glucose concentration, said test
- strip comprising:
- (a) a porous matrix;
- (b) a glucose oxidation based signal producing system comprising:
- (i) a glucose oxidase;
- (ii) a peroxidase;
- and
- (iii) an indicator that is converted to a chromogenic product in the presence of hydrogen peroxide and said peroxidase;
- and
- (c) at least one hemolyzing agent in an amount sufficient to produce hemolysis which is equivalent to hemolysate concentration in a physiological sample applied to said porous matrix in an amount ranging from about 5 to 20% by volume.
Dependencies are inferred from the claim text.