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US 6,485,920 B1Granted
Growth factor antagonist materials and methods
AssigneeHyseq, Inc.
InventorsDennis G. Ballinger, Julie Reeder Montgomery
Life of this patent
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Abstract
The present invention provides nucleic acids encoding Sprouty related human growth factor antagonist proteins (designated FGFAn-Hy), the polypeptides encoded by these nucleic acids and uses of these and related products.
Claims2
A method for identifying a compound that binds to a polypeptide consisting essentially of SEQ ID NO:
- 2, comprising:
- a) contacting a compound with the polypeptide for a time period sufficient to form a polypeptide/compound complex;
- and
- b) detecting the complex, wherein detection of the complex indicates identification of a compound that binds to the polypeptide.
1 more element
A method for identifying a compound that binds to a polypeptide consisting essentially of SEQ ID NO:
- 2, comprising:
- a) contacting a compound with the polypeptide for a time period sufficient to form a polypeptide/compound complex, wherein formation of the complex results in a detectable change in phenotype;
- b) detecting the change in phenotype, wherein the phenotype is selected from the group consisting of proliferation and angiogenesis;
- and wherein detection of the change in phenotype indicates identification of a compound that binds to the polypeptide.
1 more element
Dependencies are inferred from the claim text.