Method for treatment of chronic venous insufficiencies using an extract of red vine leaves
AssigneeBoehringer Ingelheim International GmbH
InventorsAnke Esperester, Hans W. Frey, Jean-Michel Vix
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Abstract
To prevent and/or alleviate the discomfort of mild-to-moderate chronic venous insufficiency of the lower extremities, the dietary supplement should be taken in dosages corresponding to 80-1000 mg of extract, preferably 300-800 mg, in particular 350-750 mg daily. The total amount of extract may be divided up in 1 to 3 capsules or tablets a day (or an equivalent dose by means of a liquid form). The daily dose should be taken at once, preferably in the morning.
Claims14
A method for the prevention or treatment of the discomfort associated with early stages of chronic venous insufficiency of the lower extremities, comprising oral administration to a person in need thereof an effective amount of a dietary supplement, wherein said dietary supplement comprises an active principle and a pharmaceutically, cosmetically or dietetically acceptable carrier, and wherein said active principle consists essentially of an aqueous extract of red vine leaves, and wherein said extract contains at least 2 and up to 20% flavonoids and is obtainable by a method comprising the steps of:
- (a) collecting red vine leaves at a point of time when the content in flavonoids has reached an optimum;
- (b) drying and crushing the leaves;
- (c) cutting the leaves to pieces;
- (d) extracting the leaves with water at temperatures from 60 to 80° C. for 6 to 10 hours;
- and
- (e) optionally, concentrating the obtained extract.
Dependencies are inferred from the claim text.