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US 6,485,723 B1Granted
Enhanced submucosal tissue graft constructs
AssigneePurdue Research Foundation
InventorsStephen F. Badylak, Christina Lindberg, George B. Boder, Sherry Voytik-Harbin
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Abstract
An improved tissue graft construct comprising submucosa of a warm-blooded vertebrate and a preselected group of eukaryotic cells are described. The improved tissue graft constructs can be used in accordance with the present invention to enhance the repair of damaged or diseased tissues in vivo.
Claims9
An improved tissue graft construct comprising
- vertebrate submucosa delaminated from both the external smooth muscle layers and the luminal portions of the tunica mucosa and
- added primary cells.
An improved tissue graft construct comprising
- tunica submucosa delaminated from both the tunica muscularis and at least the luminal portion of the tunica mucosa of vertebrate intestinal tissue, and
- a population of endothelial cells.
An improved tissue graft construct comprising
- vertebrate submucosa delaminated from both the external smooth muscle layers and the luminal portions of the tunica mucosa and
- added endothelial cells.
Dependencies are inferred from the claim text.