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US 6,485,707 B2Granted
Modulated release particles for aerosol delivery
AssigneeAeropharm Technology Incorporated
InventorsYaping Zhu, Akwete L. Adjei
Life of this patent
Estimating the term…
Abstract
A modulated release aerosol formulation is disclosed. The formulation comprises a polymer, e.g. Silica gel, fumed silica gel, having a selected medicament associated therewith, and a fluid carrier for carrying and delivering the construct.
Claims17
A modulated release aerosol formulation, which consists essentially of:
- a. a polymeric construct comprising a polymer selected from the group consisting of silica gel, fumed silica gel, silicic acid, disilicic acid, trisilicic acid, metasilicic acid, and orthosilicic acid, in their free or salt forms;
- silicon dioxide in either of its amporphous, crystalline, or precipitated forms;
- talc;
- attapulgite;
- micas;
- montmorilonite;
- kaolin;
- aluminum oxide;
- bentonite;
- pumice;
- silanes;
- siloxanes and a mixture of any of the foregoing polymers;
- and
- b. a biotherapeutic medicament associated with said construct.
11 more elements
A modulated release aerosol formulation, which consists essentially of:
- a. a selected particulate medicament;
- b. a polymer selected from the group consisting of silica gel, fumed silica gel, silicic acid, disilicic acid, trisilicic acid, metasilicic acid, and orthosilicic acid, in their free or salt forms;
- silicon dioxide in either of its amporphous, crystalline, or precipitated forms;
- talc;
- attapulgite;
- micas;
- montmorilonite;
- kaolin;
- aluminum oxide;
- bentonite;
- pumice;
- silanes;
- siloxanes, having said medicament associated therewith;
- and
- c. a fluid carrier for carrying and transporting said particles of said associated polymer.
12 more elements
A metered dose formulation containing a medicinal formulation, the formulation consisting essentially of:
- a. a particulate medicament in a therapeutically effective amount;
- b. a polymer selected from the group consisting of silica gel, fumed silica gel, silicic acid, disilicic acid, trisilicic acid, metasilicic acid, and orthosilicic acid, in their free or salt forms;
- silicon dioxide in either of its amporphous, crystalline, or precipitated forms;
- talc;
- attapulgite;
- micas;
- montmorilonite;
- kaolin;
- aluminum oxide;
- bentonite;
- pumice;
- silanes;
- siloxanes, or any mixture of the foregoing polymers with which said particulate medicament is associated to form a particulate polymeric construct;
- and
- c. a fluid carrier for carrying and transporting said particles of said associated polymer.
12 more elements
A modulated release formulation, which consists essentially of:
- a. a polymeric construct comprising a polymer selected from the group consisting of silica gel, fumed silica gel, silicic acid, disilicic acid, trisilicic acid, metasilicic acid, and orthosilicic acid, in their free or salt forms;
- silicon dioxide in either of its amporphous, crystalline, or precipitated forms;
- talc;
- attapulgite;
- micas;
- montmorilonite;
- kaolin;
- aluminum oxide, bentonite;
- pumice;
- silanes;
- siloxanes and a mixture of any of the foregoing polymers;
- b. a biotherapeutic medicament associated with said construct;
- c. a second medicament with which said biotherapeutic medicament is combined;
- and
- d. a fluid carrier for carrying and transporting said construct.
12 more elements
Dependencies are inferred from the claim text.