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AssigneeDelRx Pharmaceutical Corp.
InventorsRandall McCoy, Miles Augustus Libbey, III, Jle Liu, Robert O. Williams, III
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A formulation for non-invasive delivery of pharmaceutical agents, particularly proteins and peptides, by absorption through a membrane at a targeted site is provided, along with a process of making the formulation. The formulation comprises a suspension of solid-phase dehydrated particles in a delivery medium. The particles comprise the dehydration product of the pharmaceutical agent and at least one of a surfactant and permeation enhancer, and the delivery medium preferably comprises a propellant for pressurized aerosol delivery of the formulation. The formulation can be conveniently delivered to the patient's targeted site where the pharmaceutical agent is absorbed through the mucosa to achieve a desired bioavailability.
A formulation for systemic delivery of insulin to a patient through the buccal mucosa, the formulation comprising:
A process for preparing a formulation for delivering a insulin to the buccal mucosa of a patient, the process comprising
A method for systemic buccal administration of insulin to a patient in need of such treatment comprising:
Dependencies are inferred from the claim text.