Medical radioactive iodine-125 miniature radiation sources and methods of producing same
AssigneeEurotope Entwicklungsgesellschaft fur Istopentechnologien mbH
InventorsJürgen Ziegler, Claudia Müller, Gunnar Mann, André Hess
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Abstract
The present invention relates to new radioactive iodine-125 miniature radiation sources (seeds) comprising a radioactive carrier matrix which consists of a porous and mechanically stable inorganic material, the pores of which contain inorganic insoluble iodide-125, and which is enclosed within a capsule made of a corrosion-resistent and body-compatible material or which is coated with such a material. The iodine seeds according to the present invention further may contain (a) usual X-ray marker(s). Another object of the present invention are methods for manufacturing said novel iodine-125 seeds.
Claims15
A medical radioactive iodine-125 miniature radiation source, comprising a radioactive carrier matrix which emits radiation in a controlled manner, the carrier matrix being formed of a porous and mechanically stable inorganic material chosen from the group consisting of TiO2, Al2O3, ZrO2, Y2O3, and mixtures thereof, the pores of which contain inorganic insoluble iodide-125, which carrier matrix is enclosed in a corrosion-resistant and human body-compatible material, which material is transparent for the radiation emitted from the carrier matrix, and resistant to said radiation.
Dependencies are inferred from the claim text.