In Situ concentration of an analyte
AssigneeAgilent Technologies, Inc.
InventorHarry F. Prest
Life of this patent
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Abstract
An apparatus and method for selectively concentrating an analyte on an apparatus by evaporating solvent from the analyte. Concentration is performed by heating or by flowing a gas stream over the analyte to evaporate solvent from the analyte. The invention also provides a method to be used in conjunction with the apparatus.
Claims24
An apparatus for concentration of analyte in a solvent in a gas chromatograph, comprising:
- (a) a dispensing means for holding and dispensing said analyte in said solvent;
- (b) an injection means designed for receiving said dispensing means;
- and
- (c) a concentration means in contact with said injection means for concentrating said solvent in said analyte on said dispensing means in said gas chromatograph.
An apparatus for applying a gas to concentrate an analyte in a solvent in a gas chromatograph, comprising:
- (a) a syringe having a syringe needle and syringe needle tip for concentrating said analyte in said solvent;
- (b) a pre-column inlet having an inlet port for receiving said syringe needle and syringe needle tip;
- and
- (c) a gas inlet disposed in said pre-column inlet and designed so that when said syringe needle and syringe needle tip are inserted into said pre-column inlet, said syringe needle tip is positioned below said gas inlet wherein said gas causes said analyte solvent to evaporate and concentrate said analyte at said syringe needle tip.
An apparatus for concentrating an analyte in a solvent in a gas chromatograph, comprising:
- (a) a syringe with a syringe needle and tip for concentrating said analyte in said solvent;
- (b) a pre-column inlet having an inlet port for receiving said syringe needle and tip;
- and
- (c) a concentration means disposed in said pre-column inlet for concentrating said analyte in said solvent at said tip of said syringe needle in said gas chromatograph.
A method of removing solvent and concentrating an analyte in a chromatograph, comprising the steps of:
- (a) collecting the analyte in a dispensing means;
- (b) inserting the dispensing means into an injecting means;
- (c) applying a concentration means to evaporate said solvent from said analyte to concentrate said analyte on said dispensing means.
A method of concentrating an analyte in a solvent on a syringe needle tip after insertion into a pre-column inlet, comprising:
- (a) collecting said analyte in said solvent in said syringe needle tip;
- (b) inserting said syringe needle tip into said pre-column inlet;
- (c) applying a stream of gas to said analyte to evaporate said solvent of said analyte and concentrate said analyte on said syringe needle tip.
A method of concentrating an analyte in a solvent in a syringe needle tip after insertion into a pre-column inlet, comprising:
- (a) collecting said analyte in said solvent in said syringe needle tip;
- (b) inserting said syringe needle into said pre-column inlet;
- and
- (c) applying heat to said analyte to evaporate said solvent of said analyte and concentrate said analyte on said syringe needle tip.
A method of concentrating an analyte in a solvent on a syringe needle tip after insertion into a a pre-column inlet, comprising:
- (a) inserting said syringe needle tip into said inlet;
- (b) flowing said analyte in solvent onto said syringe needle tip;
- and
- (c) evaporating said solvent of said analyte to concentrate said analyte on said syringe needle tip.
Dependencies are inferred from the claim text.