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US 6,484,556 B1Granted
Thin film detection during fluid aspiration
AssigneeOrtho-Clinical Diagnostics, Inc.
InventorsMerrit Jabobs, Michael Avdenko, Christopher Michael Parobek, Jim Shaw
Life of this patent
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Abstract
The accurate determination of the presence of a fluid in a container is determined by assessing the difference in various pressure readings relative to a threshold value. The method distinguishes between actual aspiration of a fluid and aspiration of a film that can otherwise lead one to believe that fluid has been aspirated when it has not. The method is particularly useful in clinical analyzers such as automated enzyme immunoassay devices.
Claims3
A method for determining whether a fluid has been properly aspirated into a fluid container comprising:
- a) determining the pressure inside the gas filled container during initial aspiration of the fluid;
- b) determining the pressure inside the container while dispensing a portion of the fluid;
- c) determining the pressure inside the container at some time other than during step a) to establish a reference pressure;
- d) determining the difference between the value attained in step a) and the reference pressure;
- e) determining the difference between the reference pressure and the value attained in step b);
- and
- g) indicating that a thin film of fluid has been aspirated if the absolute values obtained in step d) or step e) are less than a predetermined threshold wherein the threshold is determined statistically as the CpK that is acceptable for a given false positive and/or false negative rate.
4 more elements
Dependencies are inferred from the claim text.