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AssigneeHuman Genome Sciences, Inc.
InventorsGeorge Komatsoulis, Craig A. Rosen, Steven M. Ruben, Roxanne D. Duan, Paul A. Moore, Yanggu Shi, David W. LaFleur, Ying-Fei Wei, Jian Ni, Kimberly A. Florence, Paul Young, Laurie A. Brewer, Daniel R. Soppet, Gregory A. Endress, Reinhard Ebner, Henrik Olsen, Michael Mucenski
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The present invention relates to novel human secreted protein (HNFGF20). Polypeptides of the invention are duseful in dianosis and treatment of disorders affecting the immune system.
An isolated protein comprising amino acid residues 46 to 143 of SEQ ID NO:194.
An isolated first polypeptide at least 90% identical to a second polypeptide comprising amino acid residues 46 to 143 of SEQ ID NO:194, wherein said first polypeptide stimulates the proliferation of bone marrow CD34+ cells.
An isolated protein consisting of at least 30 contiguous amino acid residues of amino acid residues 46 to 143 of SEQ ID NO:194.
An isolated protein consisting of at least 30 contiguous amino acid residues of amino acid residues 1 to 143 of SEQ ID NO:194.
An isolated protein consisting of at least 30 contiguous amino acid residues of toe complete polypeptide encoded by the HNFGF20 cDNA contained in ATCC Deposit No. 203071.
An isolated first polypeptide at least 90% identical to a second polypeptide comprising amino acid residues 1 to 143 of SEQ ID NO:194, wherein said first polypeptide stimulates the proliferation of bone marrow CD 34+ cells.
An isolated recombinant protein produced by the method comprising:
An isolated first polypeptide at least 90% identical to i second polypeptide comprising the complete polypeptide encoded by the HNFGF20 cDNA contained in ATCC Deposit No. 203071, wherein said first polypeptide stimulates the proliferation of bone marrow CD 34+ cells.
Dependencies are inferred from the claim text.