NLK1 protein and NLK1 protein complexes

A chimeric protein comprising a fragment of an Nlk1 protein consisting of at least 6 amino acid residues fused, via a covalent bond to a fragment of Nlk1 protein-IP also consisting of at least 6 amino acid residues, wherein said Nlk1 protein-IP is selected from the group consisting of TrkA, protein phosphatase 1α, 14-3-3ε, α-tropomyosin, vimentin, p0071, Ini-1, IP-1 (SEQ ID NO:18), IP-2 (SEQ ID NO:20), IP-3 (SEQ ID NO:22), IP-4 ((SEQ ID NO:24) and IP-5 (SEQ ID NO:26), and wherein said fragment of the Nlk1 protein is a fragment that binds to the Nlk1 protein-IP and wherein said fragment of the Nlk1 protein-IP is a fragment capable of binding the Nlk1 protein.

A purified IP selected from the group consisting of IP-1 (SEQ ID NO:18), IP-2 (SEQ ID NO:20), IP-3 (SEQ ID NO:22), IP-4 (SEQ ID NO:24) and IP-5 (SEQ ID NO:26).

A purified protein encoded by a nucleic acid which is hybridizable under high stringent hybridization condition to the inverse complement of a DNA possessing a nucleotide sequence comprising at least 10 nucleotides of the nucleotide sequence selected from the group consisting of SEQ ID NO:17;

• SEQ ID NO:19;
• SEQ ID NO:21;
• SEQ ID NO:23, and SEQ ID NO:25, wherein the encoded protein binds the Nlk1 protein.

A purified fragment of a protein selected from the group consisting of:

• TrkA, protein phosphatase 1α, 14-3-3ε, α-tropomyosin, vimentin, p0071, Ini-1, IP-1 (SEQ ID NO:18), IP-2 (SEQ ID NO:20), IP-3 (SEQ ID NO:22), IP-4 (SEQ ID NO:24) and IP-5 (SEQ ID NO:26), wherein said fragment possesses the ability to bind the Nlk1 protein.

A kit comprising a Nlk1 protein and aNlk1 protein-IP, wherein said Nlk1 protein-IP is selected from the group consisting of:

• TrkA, protein phosphatase 1α, 14-3-3ε, α-tropomyosin, vimentin, p0071, Ini-1, IP-1 (SEQ ID NO:18), IP-2 (SEQ ID NO:20), IP-3 (SEQ ID NO:22), IP-4 (SEQ ID NO:24) and IP-5 (SEQ ID NO:26).